Central Precocious Puberty

What is central precocious puberty?

Central precocious puberty is a condition that causes an early onset of puberty in children: before 8 years of age in girls and 9 in boys. It’s not always clear what causes early puberty, and it may just be a tendency that runs in the family. Treatment with medication is usually only recommended if it’s thought early puberty will cause emotional or physical problems, such as a very short stature or early periods in girls, which may cause significant distress.

How does Prostap DCS work?

The changes associated with puberty occur as a result of hormonal changes within the body, specifically an increase of oestrogen in girls and testosterone in boys. Prostap DCS allows for a delayed onset of puberty by reducing the levels of oestrogen and testosterone produced in the body.

How is your medication given?

Prostap DCS is an injection. It will be prepared according to your dosage needs and administered by your nurse or doctor at your GP surgery or hospital. You will have been prescribed one of three versions of Prostap DCS. These different types contain different amounts of the active medicine, which will determine the frequency you are given the injection.

Most common side effects

Injection-site reaction
Skin reactions at the site of the injection are common, affecting up to 1 in 10 children.
These include:

• Skin hardening
• Redness
• Pain
• Abscesses
• Swelling
• Nodules
• Ulcers
• Skin damage

Note:
When your child begins treatment with Prostap PD DCS, existing symptoms may initially get worse as a result of levels of sex steroids in the body increasing. These worsening symptoms usually subside with continued use of Prostap PD DCS.

Other side effects
For a full list of side effects, please consult the patient information leaflet for your dose. If you don’t have a copy of the patient information leaflet you can download one here:

Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet or the package leaflet. Please don’t skip an injection.

You can also report side effects directly via the Yellow Card Scheme at mhra.gov.uk/yellowcard

By reporting side effects, you can help provide more information on the safety of Prostap DCS.